Science - Chemistry 2 & 3 - Organic & Analytical Chemistry: Assignment: Exercise 1

1a. Using the Combine Chemical Dictionary Online, find and write down the:

CAS Registry Number; Molecular Formula and Biological use for these Organic Compounds:

• Aspirin
• Cocaine
• Morphine: Variant (-)-form
• Nicotine: Variant (S)-form

1 c. Use Merck Index (13th & 14^th ed.) to find the following information:

 Handwritten - Draw the Structure; Write the Medical use/Use and Primary  Literature Reference (is the 1^st entry, the earliest in the “literature reference”) of:

• Tocol
• Quinine
• Nicotine
• Monensin
• Lidocaine

Help Tips:

The PRIMARY LITEARTURE REFERENCE is the 1^st entry (the earliest) in the “literature reference”. For “tocol” the Primary reference is: Pendse, Karrer, Helv. Chim. Acta 40, 1837 (1957).

MEDICAL USE/ USE information is usually available at the end of the entry under the “Therapeutic category”. For “quinine” the medical use is: Antimalarian, muscle relaxant (skeletal)

1 b. Use the Print Handbook of Chemistry & Physics (100th ed)  or the Online 103th ed of Handbook of Chemistry & Physics to find the Structure and the Boiling point of the following compounds:

• 1-Methyl-1H-pyrazole
• 2-Methyl-1-pentanol
• 1,3-Benzenediamine
• 1,4-Diisopropylbenzene
• 2-Amino-2-methyl-1-propanol

Step 1: Find Section 3: Physical Constants of Organic Compounds

Step 2: Search for each of the compounds on the list

Step 3: Handwritten - Draw the Structure and write the Boiling point of each of the compounds above

1 d. Use Merck Index to find the following information:

Find the following reactions:

Handwritten: DRAW the Reaction Structure and WRITE the Primary Reference of:

• Friedel-Crafts reaction
• Michael reaction
• Perkin reaction
• Suarez reaction
• Wittig reaction

Help:

From the Table of Contents in Merck’s Index find the “Organic Name Reactions”. The reactions are in Alphabetical order.